Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Kainzbauer, N.
BIPOLAR DISORDER AND PHYSICAL ACTIVITY -
Correlation between physical activity and clinical parameters in bipolar disorder
Humanmedizin; [ Diplomarbeit ] Graz Medical University; 2016. pp.
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- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Fellendorf Frederike
- Reininghaus Eva
- Altmetrics:
- Abstract:
- Introduction: A high number of co-morbidities (Co-M) and increased mortality accompany bipolar disorder (BD). Especially Overweight and Obesity, systemic inflammatory processes and cognitive deficits are highly prevalent and increase within the course of illness. Physical activity (PA) was found to have beneficial effects not only on psychiatric symptoms, but also on Co-M such as reduced weight, better neurocognitive performance and reduced inflammation in former studies. Aim: The aim of the study is to identify correlates of PA in patients suffering from BD that influence the course of the disease. Moreover, the PA behaviour of patients was compared to healthy controls. Methods and Participants: 119 patients, euthymic at point of testing, and 71 healthy controls completed the self-reported “International Physical Activity Questionnaire (IPAQ)” interrogating PA of the past seven days. Furthermore, inflammatory biomarkers and clinical parameters were gathered. Results: There was no difference in the self-reported PA behaviour between patients and controls. Body Mass Index (BMI), global functioning (GAF) and cognitive parameters such as attention, memory and executive functioning correlate with PA in BD. Inflammatory markers, clinical presentation of BD and premorbid IQ are not correlated to PA in the cohort. Conclusion: A positive correlation between PA and BMI, attention, memory, executive functioning and GAF were found. However, the study could not support previous findings suggesting that PA correlates with inflammatory state of body and clinical parameters. In conclusion, sport seems to offer a concomitant therapy, as it is ncorrelated to cognitive functioning and weight. However, further data concerning PA from a less subjectivity prone questionnaire investigating PA behaviour over a longer period are necessary to verify past findings.