Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Wurm, M.
Histogram analysis of lung CT scans of pulmonary
hypertension patients
Humanmedizin; [ Diplomarbeit ] Medical University of Graz; 2014. pp. 59
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- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Balint Zoltan
- Olschewski Andrea
- Altmetrics:
- Abstract:
- The evaluation of the X-ray attenuation in the lung parenchyma by histogram analysis can give relevant information to quantify pathologic changes in the lung. The main goal of this thesis is to develop an algorithm for lung CT image analysis and to identify diagnostically relevant parameters for pulmonary hypertension (PH) and associated lung diseases, via correlation with patient clinical data. In a clinical CT study of 25 patients we retrospectively applied an automated algorithm to provide statistical information of the lung parenchyma of them. Quantitative readouts of lung parenchyma histograms of patients with and without PH were computed. Statistical analysis has been performed of Hounsfield units and lung perfused blood volume and histograms, skewness, kurtosis, full-width at half-maximum and normalized peak height have been compared. We found specific quantitative parameters of perfused blood volume histograms to differentiate between PH and non-PH patients in our patient cohort.