Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Trimmel, V.
Gestational diabetes mellitus and its long-term consequences for the mother and her offspring
[ Diplomarbeit ] Medical University of Graz; 2009. pp.56
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- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Wadsack Christian
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- Abstract:
- The following thesis is dealing with gestational diabetes mellitus and the long-term consequences for the mother and her offspring. Evidence based studies suggest that the risk for developing type 2 diabetes mellitus and metabolic syndrome later in life is more pronounced by mothers who suffered from GDM during pregnancy. In order to analyze which long-term consequences for mother and child are reliable selective studies were compared. The overall questions are: 1. Which diagnostic criteria are determined for long-term consequences within the different studies? 2. Are any screening similarities between the selected studies observable? The analyzed and compared studies related to the mother observed primarily glucose tolerance tests during and after pregnancy for demonstrating the increased incidence of Type 2 diabetes mellitus after gestational diabetes mellitus. In addition diverse criteria for the metabolic syndrome were also measured. Although different sizes of study groups were studied for a different long time period, the maternal risk of developing Type 2 diabetes mellitus or metabolic syndrome after gestational diabetes mellitus is conformable significantly increased. Studies which investigated the increased risk for developing Type 2 diabetes mellitus or metabolic syndrome for the offsprings later in life, used mainly the birth weight as a predictor for obesity. Most of the authors studied the offsprings of the mothers with previous gestational diabetes mellitus for a longer time period, therefore a correlation with higher significance between gestational diabetes mellitus and the later development of the metabolic syndrome for the child could be observed. Although different analytical methods were used, the elementary findings are the same. This is valid for the studies about the mother as well for the off-spring. The investigated studies indicate that the risk for developing type 2 diabetes mellitus and metabolic syndrome are significantly elevated for mother and child.