Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Bezan, A.
Haemodynamics and autonomic nervous system activity in patients with essential hypertension, influence of age and sex
[ Dissertation ] Medical University of Graz; 2006. pp.
- Autor*innen der Med Uni Graz:
- Terbuch Angelika
- Betreuer*innen:
- Pessenhofer Herfried
- Altmetrics:
- Abstract:
- The autonomic nervous system (ANS) plays an important role in cardiovascular control. A dysfunktion of autonomic nervous regulation can lead to symptoms like dizziness, postural hypotension or even syncope. Tilt table investigations are used to show alterations of the ANS by recording haemodynamic variables and calculating parameters or the ANS. The Task Force Monitor is an non-invasive, real time and beat-to-beat monitoring system. It combines electrocardiography, impedance cardiography, continuous blood pressure measurement and oscillometric blood pressure measurement for calibration of the beat-to-beat values. Power spectral analysis of heart rate and blood pressure variability gives information about sympathetic and vagal tone and baroreflex sensitivity can be calculated. The present study was undertaken to clarify if essential hypertension can lead to alterations of the autonomic nervous system. Therefore the haemodynamic data of 20 patients with essential hypertension were compared to those of 21 healthy, normotensive patients. Furthermore the influence of age on the ANS was shown by splitting the normotensive into tow groups with an age difference of at least 29 years. The final step was to clarify if there exist any gender differences. The Task Force Monitor is a non-invasive method that gives real time and beat-to-beat informations about haemodynamic and autonomic nervous functions in a very convenient way for the patient.