Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Kroneis, B.
Early outcomes in patients with oesophageal atresia
[ Dissertation ] Medical University of Graz; 2007. pp.
- Autor*innen der Med Uni Graz:
- Betreuer*innen:
- Hauer Almuthe
- Höllwarth Michael
- Altmetrics:
- Abstract:
- Approach and methods have changed since oesophageal atresia (OA) was first described in literature and successfully treated by primary anastomosis fort he first time. The treatment of children with this malformation is still a challenge in paediatric surgery. The aim of this study was evaluating the outcome and analysing early complications and sequelae, which followed the repair of oesophageal atresia. Methods: data of 99 patients with OA with or without tracheo-oesophageal fistula (TOF), which were initially treated at the Department of Paediatric Surgery, Medical University of Graz from January 1975 to December 2005 was collected and reviewed. To show changes over time cases were divided in two groups: GROUP-I (n=55) 1975-1989, GROUP-II (n=44) 1990-2005). Patients were classified according to Waterston and Spitz. Information about birth, type of OA, associated anomalies, surgical treatment, complications, sequelae, mortality and cause of death was obtained for all patients. Results: The oberall survival rate was 82,8%. Survival rates of premature patients, patients with assoviated anomalies and patients with preoperative pneumonia increased during study-period. Time of first hospitalisation, time spent at the intensive care unit and need of mechanical ventilation decreased. Fewer patient with early postoperative complications (stricture, leak, recurrent fistula) were found in GROUP-II, but more with reflux and/or tracheomalacia. Conclusio: Today the successful management of OA is possible in most of the cases. Unavoidable death is caused by severe associadet anomalies, especially by major cardiac defects and other lethal malformations. Survivors mainly suffer from oesophageal dysmotolity and gastro-oesophageal reflux.