Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Becker, JC; Ugurel, S; Schrama, D.
Strategies to optimize the use of targeted agents for tumor therapy.
J Dtsch Dermatol Ges. 2008; 6(4):281-285
Doi: 10.1111/j.1610-0387.2008.06496.x
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- Führende Autor*innen der Med Uni Graz
- Becker Jürgen Christian
- Schrama David
- Co-Autor*innen der Med Uni Graz
- Ugurel-Becker Selma
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- Abstract:
- In recent years the traditional treatment spectrum of tumors--chemotherapy or radiotherapy--has been extended with immune-modulating strategies. For some tumors, clinical responses have been observed but for numerous others no satisfactory approach has been established. Many new agents have been developed; the targeted or smart drugs modulate a constantly growing list of tumor-specific signal pathways and represent an enormous hope for cancer patients. The clinical evaluation of these targeted drugs alone or in combination also presents an enormous challenge. Since the number of possible combinations of targeted drugs seems almost limitless, an accurate strategy for determination of success-promising combination patterns for the individual cancer patient is of special importance.
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- Find related publications in this database (Keywords)
- cancer
- targeted drugs
- combination therapy
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- signal transduction