Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Reich, O; Regauer, S; Scharf, S.
High levels of xenoestrogens in patients with low-grade endometrial stromal sarcoma - report of two cases
EUR J GYNAECOL ONCOL. 2010; 31(1): 105-106.
Web of Science
- Führende Autor*innen der Med Uni Graz
- Reich Olaf
- Co-Autor*innen der Med Uni Graz
- Regauer Sigrid
- Altmetrics:
- Abstract:
- Background: Endometrial stromal sarcomas (ESS) are rare uterine tumors with unknown etiological risk factors, but estrogen-dependent growth promotion. Cases: We present two patients with advanced ESS, who had increased levels of p,p-DDE hexachlorobenzene; PCB 28 PCB 52; PCB 101; PCB 138; PCB 153 and PCB 180 in abdominal adipose tissue. Other xenoestrogens were within expected limits for the non-exposed European population. Conclusion: Increased levels of xenoestrogens in patients with ESS may be involved in the pathogenesis of ESS. Chronic exposure to xenoestrogens may be a risk factor for tumor progression.
- Find related publications in this database (Keywords)
- Endometrial stromal sarcoma
- Estrogen
- Xenoestrogen
- Pathogenesis