Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Mohamad Al-Ali, B; Trummer, H; Shamloul, R; Zigeuner, R; Pummer, K.
Is treatment of hemorrhagic radiation cystitis with hyperbaric oxygen effective?
Urol Int. 2010; 84(4): 467-470.
Doi: 10.1159/000296289
Web of Science
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- Führende Autor*innen der Med Uni Graz
- Mohamad Al-Ali Badereddin
- Co-Autor*innen der Med Uni Graz
- Pummer Karl
- Zigeuner Richard
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- Abstract:
- Objective: We report our own experience with the use of hyperbaric oxygen (HBO) for the management of postradiation hemorrhagic cystitis. Methods: We reviewed retrospectively 14 patients from 2001 to 2007 with different pelvic organ malignancies who developed radiation cystitis after irradiation. Patients received 100% oxygen in a hyperbaric chamber at a pressure of 2.5 atmospheres absolute, 60 min bottom time, once a day, 7 days a week for at least 1 month. In principle, 30 HBO treatments per course were performed. After every course of HBO treatments, therapeutic effect was evaluated. The mean duration of follow-up of all patients was 18 months (range: 1-6 years). Results: Patients were divided into 2 groups, group 1 (treatment group, n = 10) and group 2 (without treatment, n = 4). The mean duration between the onset of hematuria and the beginning of HBO therapy was 8.9 months (range: 3-34). Group 2 did not receive HBO because they were not healthy enough. Only 2 patients (20%) of group 1 recovered from their hemorrhagic cystitis. Group 1 had a significantly lower cure rate of postirradiation hemorrhagic cystitis in comparison to group 2. Conclusions: Our experience with the use of HBO did not yield favorable results. Randomized well-controlled studies are needed. Copyright (C) 2010 S. Karger AG, Basel
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Aged, 80 and over -
- Cystitis - etiology
- Female -
- Hematuria - etiology
- Hemorrhage - etiology
- Humans -
- Hyperbaric Oxygenation -
- Male -
- Middle Aged -
- Pelvis -
- Radiation Injuries - etiology
- Radiotherapy - adverse effects
- Retrospective Studies -
- Time Factors -
- Treatment Outcome -
- Find related publications in this database (Keywords)
- Hyperbaric oxygen
- Hemorrhagic cystitis
- Irradiation
- Pelvic organ malignancies