Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

KERL, H.
THE 3RD INTERNATIONAL DERMATOPATHOLOGY SYMPOSIUM CONCERNING MALIGNANT-MELANOMA AND OTHER NEUROSCRISTOPATHIES HELD IN LIEGE, BELGIUM, AUGUST 11-15, 1984
AMER J DERMATOPATHOL. 1985; 7(1): 93-94. Doi: 10.1097/00000372-198502000-00020
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Führende Autor*innen der Med Uni Graz
Kerl Helmut
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Abstract:
We re-examined histologic sections of 305 melanocytic lesions consecutively received for diagnosis in 1978. Of 237 lesions previously diagnosed as banal melanocytic nevi, 28% were reinterpreted to be dysplastic nevi. Clinical follow-up 5 years later of 28 incompletely removed dysplastic nevi revealed neither persistence of pigment nor development of malignant melanoma at their sites of biopsy. We conclude, therefore, that dysplastic melanocytic nevi were common melanocytic neoplasms in 1978. Furthermore, based on our findings, they may be managed safely by observation with periodic clinical follow-up. Of 61 malignant melanomas studied during the same period in 1978, none occurred in association with a dysplastic nevus. The concept that malignant melanomas commonly arise in dysplastic melanocytic nevi therefore should be re-examined.
Find related publications in this database (using NLM MeSH Indexing)
Diagnosis, Differential -
Dysplastic Nevus Syndrome - pathology
Epidermis - pathology
Humans -
Hyperplasia -
Melanocytes - pathology
Melanoma - pathology
Neoplasms, Multiple Primary - pathology
Nevus, Pigmented - pathology
Retrospective Studies -
Skin - pathology
Skin Neoplasms - pathology

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