Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Balassy, C; Kasprian, G; Brugger, PC; Weber, M; Csapo, B; Mittermayer, C; Hörmann, M; Prayer, D.
MRI investigation of normal fetal lung maturation using signal intensities on different imaging sequences.
Eur Radiol. 2007; 17(3):835-842
Doi: 10.1007/s00330-006-0409-9
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Csapo Bence Daniel
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- Abstract:
- To purpose of this paper is to study the relation between normal lung maturation signal and changes in intensity ratios (SIR) and to determine which magnetic resonance imaging sequence provides the strongest correlation of normal lung SIs with gestational age. 126 normal singleton pregnancies (20-37 weeks) were examined with a 1.5 Tesla unit. Mean SIs for lungs, liver, and gastric fluid were assessed on six different sequences, and SIRs of lung/liver (LLSIR) and lung/gastric fluid (LGSIR) were correlated with gestational age for each sequence. To evaluate the feasibility of SIRs in the prediction of the state of the lung maturity, accuracy of the predicted SIRs (D*) was measured by calculating relative residuals (D*-D)/D for each sequence. LLSIRs showed significant changes in every sequence (p<0.05), while LGSIRs only on two sequences. Significant differences were shown for the mean of absolute residuals for both LLSIRs (p<0.001) and for LGSIRs (p=0.003). Relative residuals of LLSIRs were significantly smaller on T1-weighted sequence, whereas they were significantly higher for LGSIRs on FLAIR sequence. Fetal liver seems to be adequate reference for the investigation of lung maturation. T1-weighted sequence was the most accurate for the measurement of the lung SIs; thus, we propose to determine LLSIR on T1-weighted sequence when evaluating lung development.
- Find related publications in this database (using NLM MeSH Indexing)
- Feasibility Studies -
- Female -
- Fetal Development -
- Fetal Organ Maturity -
- Gastric Juice - physiology
- Gestational Age -
- Humans -
- Liver - embryology
- Lung - anatomy and histology Lung - embryology
- Magnetic Resonance Imaging - methods
- Pregnancy -
- Find related publications in this database (Keywords)
- MR imaging
- fetal lung
- signal intensity
- lung development