Medizinische Universität Graz - Research portal
Selected Publication:
Hofmann, HM; Weiss, PA; Pürstner, P; Haas, J; Gmoser, G; Tamussino, K; Schmon, B.
Serum fructosamine and amniotic fluid insulin levels in patients with gestational diabetes and healthy control subjects.
Am J Obstet Gynecol. 1990; 162(5): 1174-1177.
Doi: 10.1016/0002-9378(90)90010-5
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- Co-authors Med Uni Graz
- Haas Josef
- Pürstner Peter
- Tamussino Karl
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- Abstract:
- Gestational diabetic pregnancies with fetal hyperinsulinism should be identified because these cases require insulin therapy. To determine the relationship between the serum fructosamine and amniotic fluid insulin concentrations, these substances were measured in 87 pregnant women with impaired glucose tolerance. Fructosamine was also measured in 678 healthy pregnant control subjects, in 113 of whom amniotic fluid insulin levels were available. Fetal hyperinsulinism was rare at serum fructosamine levels of less than 2.6 mmol/L. These results suggest that when both the oral glucose tolerance test and fructosamine level are used, only 30% of women with gestational diabetes need to undergo amniocentesis to assess fetal insulin homeostasis.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Amniotic Fluid - metabolism
- Female -
- Fetal Diseases - diagnosis
- Fructosamine -
- Glucose Tolerance Test -
- Hexosamines - blood
- Humans -
- Hyperinsulinism - diagnosis
- Insulin - metabolism Insulin - therapeutic use
- Pregnancy - blood Pregnancy - metabolism
- Pregnancy in Diabetics - blood Pregnancy in Diabetics - metabolism Pregnancy in Diabetics - therapy