Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Pfurtscheller, K; Senning, B; Bernhard, H; Novak, M; Zobel, G; Plecko, B; Muntean, W.
Malignant stroke in an adolescent with a homozygous MTHFR 677CT mutation and intake of hormonal contraceptives
HAMOSTASEOLOGIE. 2009; 29: S84-S86.
Doi: 10.1055/s-0037-1621494
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Muntean Eugen
- Pfurtscheller Klaus
- Co-authors Med Uni Graz
- Bernhard Heike
- Novak Michael Peter
- Plecko Barbara
- Zobel Gerfried
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Severe stroke in children and adolescents with its devastating long term consequences remains a rare disorder with many open questions. Beside the well known risk factors such as infection or congenital and acquired heart disease, coagulation disorders have to be considered in the differential work up of the underlying aetiology. Here we report the case of an adolescent with a homozygote MTHFR 677CT mutation suffering a malignant stroke shortly after the start of oral contraceptives. Since prevention seems easily feasible, general screening for MTHFR mutations might be worthwhile in women before starting oral contraceptives.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Contraceptives, Oral, Hormonal - adverse effects
- Fatal Outcome -
- Female -
- Homocysteine - blood
- Humans -
- Infarction, Middle Cerebral Artery - chemically induced
- Infarction, Middle Cerebral Artery - enzymology
- Infarction, Middle Cerebral Artery - genetics
- Magnetic Resonance Imaging -
- Methylenetetrahydrofolate Reductase (NADPH2) - genetics
- Mutation -
- Find related publications in this database (Keywords)
- Stroke
- children
- methylenetetrahydrofolate reductase
- hormonal contraceptives