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Langner-Wegscheider, BJ; Wagner, J; Weger, M; Haas, A; Mayer, M; Wedrich, A.
Acute posterior placoid chorioretinitis and panuveitis in syphilis patients
SPEKTRUM AUGENHEILKD. 2009; 23(5): 358-362. Doi: 10.1007/s00717-009-0357-2
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Leading authors Med Uni Graz: Langner-Wegscheider Beate Julia
Co-authors Med Uni Graz: Haas Anton; Mayer Monika; Wagner Julia; Wedrich Andreas; Weger Martin
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Abstract:: Syphilis is a sexually transmitted disease on the rise. We report on two patients with acute posterior placoid chorioretinitis and on two others with unilateral panuveitis. PATIENTS: Patient 1 and 2 presented with unilateral decrease in visual acuity and yellowish placoid macular changes. Best-corrected visual acuity (BCVA) was tested 0.5 in patient 1 and 0.2 in patient 2, respectively. Lues serum tests revealed positive for treponema pallidum; in patient 2 the bacteria was also found in the cerebrospinal fluid. After treatment with intravenous penicillin, vision increased again to 1.0 and 0.8 in the affected eyes, respectively. Patient 3 and 4 presented with unilateral panuveitis (BCVA 0.05 and light perception respectively). In patient 4 the second eye also showed optic disc edema (BCVA 1.0). Lues serum tests revealed positive for Lues; in patient 3 the bacteria was also found in the cerebrospinal fluid. Intravenous penicillin improved vision to 1.0 and 0.5 respectively, but patient 3 also required additional parabulbar steroids started for non-clearance of vitreous haze. DISCUSSION: In characteristic posterior placoide chorioretinitis syphilis should be considered as a possible diagnosis. Syphilis can cause many forms of ocular inflammation and should be ruled out in any case of unclear ocular inflammation or unclear disc edema.
Find related publications in this database (Keywords): Syphilis; posterior placoid chorioretinopathy; panuveitis