Medizinische Universität Graz - Research portal
Selected Publication:
Hüttner, U; Kainer, F; Weiss, PA; Haas, J.
Fetal ultrasound biometry and amniotic fluid insulin concentration in pregnant diabetic patients
Gynakol Geburtshilfliche Rundsch. 1997; 37(1):21-24
Doi: 10.1159/000272803
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- Leading authors Med Uni Graz
- Haas Josef
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- Abstract:
- OBJECTIVE: The aim of the study was to prove the sensitivity of sonographic measurements for the presence of a fetal hyperinsulinism. METHODS: In a longitudinal examination of 102 insulin-dependent diabetics we show the correlation between the amniotic fluid insulin level and the biparietal diameter, abdominal diameter and femur length in the third trimester. The control of the maternal metabolic state was done by measuring the glycosylated hemoglobin and fructosamine at the time of the amniocentesis. RESULTS: The sensitivity, specificity, positive and negative predictive value of sonographic measurements > 75th percentile in fetal hyperinsulinism was for the biparietal diameter 21, 96, 81 and 62%, for the abdominal diameter 48, 82, 69 und 66%, and for the femur length 22, 90, 67 and 57%. The maternal glycoproteins did not show any correlation with the amniotic fluid insulin level. CONCLUSIONS: The results demonstrate that fetal hyperinsulinism cannot be proved by fetal biometry or evaluation of the maternal metabolic state.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Amniotic Fluid - chemistry
- Anthropometry -
- Diabetes Mellitus, Type 1 - ultrasonography
- Female -
- Fetal Macrosomia - ultrasonography
- Fructosamine - analysis
- Hemoglobin A, Glycosylated - analysis
- Humans -
- Hyperinsulinism - ultrasonography
- Infant, Newborn -
- Insulin - analysis
- Pregnancy -
- Pregnancy in Diabetics - ultrasonography
- Risk Factors -
- Ultrasonography, Prenatal -
- Find related publications in this database (Keywords)
- diabetic pregnant patients
- fetal hyperinsulinism
- amniotic fluid insulin