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Koletzko, B et al. (Recommendation group with Hauer, A; Deutsch, J).
Recommendations on pre- and probiotics in infant formula
MONATSSCHR KINDERHEILK. 2009; 157(3): 267-270.
Doi: 10.1007/s00112-008-1942-1
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Hauer Almuthe
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- Abstract:
- For some time infant formulas have been enriched with pre- and probiotics. Prebiotics are nondigestible food components that beneficially affect host health by selectively stimulating the growth or activity of a number of bacteria in the gut. Probiotics are live microorganisms capable of benefitting human health when supplied in effective doses. In healthy infants, a clinically relevant advantage of infant formulas enriched with pre- and probiotics, as compared to non-supplemented formulas, has not yet been unequivocally demonstrated. In cases where mother's milk is unavailable or insufficient, infants with heart disease, a compromised immune system or on immunosuppressive treatment should currently not be given infant formulas with probiotics due to remaining questions on safety in these risk situations. Preterm infants who cannot receive fortified human milk should receive a preterm formula without probiotics. The Committees on Nutrition support carrying out further controlled randomised trials of high scientific standards with adequate sample sizes to further evaluate the safety and efficacy of infant formulas and preterm formulas with pre- and probiotics, which should address longer term effects as far as possible.
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Prebiotics
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Probiotics
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Infant formula
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Efficacy
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Safety