Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Fazekas, F.
Magnetic resonance signal abnormalities in asymptomatic individuals: their incidence and functional correlates.
Eur Neurol. 1989; 29(3):164-168
Doi: 10.1159/000116401
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- Führende Autor*innen der Med Uni Graz
- Fazekas Franz
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- Abstract:
- MR signal abnormalities were assessed in 87 symptom-free volunteers (31-83 years of age) and correlated with cerebrovascular risk factors, cerebral blood flow and glucose metabolism. Lesions in the subcortical and deep white matter increased from 11% in the 4th decade to 83% in subjects over 70 years of age, and were detected significantly more often in individuals with cerebrovascular risk factors (p less than 0.01). They were associated with lower slow-compartmental flow (p less than 0.05) but did not affect adjacent cortical glucose metabolism. Periventricular signal changes also increased with age but were unrelated to risk factors or functional data.
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