Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
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SHR Neuro Krebs Kardio Lipid Stoffw Microb
Nickel, MK; Nickel, C; Lahmann, C; Mitterlehner, FO; Tritt, K; Leiberich, PK; Rother, WK; Loew, TH.
Changes in instrumental activities of daily living disability after treatment of depressive symptoms in elderly women with chronic musculoskeletal pain: a double-blind, placebo-controlled trial.
Aging Clin Exp Res. 2005; 17(4):293-296
Doi: 10.1007/BF03324613
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- Führende Autor*innen der Med Uni Graz
- Nickel-Palczynski Marius
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- Abstract:
- BACKGROUND AND AIMS: The purpose of this study was to assess the effect of antidepressant therapy on changes in instrumental activities of daily living disability in elderly female patients with musculoskeletal pain in a controlled study comparing active drugs with a placebo. METHODS: In an 8-week double-blind, placebo-controlled outpatient trial, 30 female patients (response rate 90.0%) between 70 and 79 were examined. They all had a history of clinically evident musculoskeletal pain, were afflicted with depressive symptoms, and could independently bathe, walk, dress, and transfer (e.g., from a chair) inside the house. The study was performed using the Center for Epidemiological Studies Depression Scale (CES-D), and Instrumental Activities of Daily Living (IADL). RESULTS: Compared with the placebo-group, significant changes in the CES-D (p<0.01) and IADL (p<0.01) scales were observed after eight weeks in the active drug-treated subjects. CONCLUSION: Treatment of depressive symptoms may be efficacious in reducing IADL disability in elderly female patients afflicted with musculoskeletal pain.
- Find related publications in this database (using NLM MeSH Indexing)
- Activities of Daily Living -
- Aged -
- Antidepressive Agents - therapeutic use
- Chronic Disease -
- Depression - drug therapy Depression - physiopathology
- Disability Evaluation -
- Double-Blind Method -
- Female -
- Geriatric Assessment -
- Health Status -
- Humans -
- Musculoskeletal Diseases - physiopathology
- Pain - physiopathology
- Pain Measurement -
- Placebos -
- Psychiatric Status Rating Scales -
- Find related publications in this database (Keywords)
- depression in elderly
- IADL disability
- treatment