Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Burghardt, E; Lahousen, M; Stettner, H.
The significance of pelvic and para-aortic lymphadenectomy in the operative treatment of ovarian cancer.
Baillieres Clin Obstet Gynaecol. 1989; 3(1):157-165
Doi: 10.1016/S0950-3552(89)80050-1
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- Co-Autor*innen der Med Uni Graz
- Lahousen Manfred
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- Abstract:
- Since 1980, 95 of 320 patients with ovarian cancer of Stages I to IV have undergone pelvic lymphadenectomy. A further 57 patients underwent pelvic and para-aortic lymphadenectomy. In the last three years, 83% of patients with Stage III disease had a lymphadenectomy, and 34% had no gross residual tumour after surgery. This entailed bowel resection in 33% of cases. After cytoreduction and chemotherapy, actuarial 5-year survival in Stages I and II was 90%, and was just over 40% in Stage III. Patients with positive nodes had markedly poorer survival than did those with negative nodes. Three years after only pelvic lymphadenectomy, 36.7% of patients with Stage III disease had no clinical, radiological or biochemical evidence of disease. If the abdomen had been cleared of gross disease at surgery, 70% of the patients had no evidence of disease at 3 years. The therapeutic effect of lymphadenectomy is also reflected in the marked improvement in survival of all patients with Stage III ovarian cancer after the introduction of lymphadenectomy.
- Find related publications in this database (using NLM MeSH Indexing)
- Chromaffin System - surgery
- Female - surgery
- Humans - surgery
- Lymph Node Excision - surgery
- Neoplasm Staging - surgery
- Ovarian Neoplasms - mortality
- Para-Aortic Bodies - surgery
- Pelvic Neoplasms - secondary
- Prognosis - secondary