Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Zacherl, M; Giessauf, C; Glehr, M; Gruber, G; Maurer-Ertl, W; Schwantzer G; Liegl-Atzwagner, B; Koch, H; Leithner, A; Windhager, R.
Revision of inadequately treated soft-tissue sarcoma is associated with increased need for plastic or reconstructive surgery.
ACTA CHIR AUST. 2009; 41(4): 155-162.
Doi: 10.1007/s10353-009-0476-7
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- Führende Autor*innen der Med Uni Graz
- Zacherl Maximilian
- Co-Autor*innen der Med Uni Graz
- Glehr Mathias
- Gruber Gerald
- Koch Horst
- Leithner Andreas
- Liegl-Atzwanger Bernadette
- Maurer-Ertl Werner
- Schwantzer Gerold
- Windhager Reinhard
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- Abstract:
- BACKGROUND: Soft-tissue sarcomas (STS) of the extremities are frequently misdiagnosed at initial presentation with a high rate of treatment not in accordance with clinical practice guidelines. The purpose of this study was to detect clinical influence of inadequate surgery prior to referral to a tumour centre. METHODS: Five-year single institution review of patients operated for STS of the extremities in a tertiary referral unit. RESULTS: A total of 116 patients underwent curative surgery for STS between 1998 and 2003. A total of 59 (51%) patients were operated contrary to current clinical guidelines before referral (group B). A total of 54 (92%) of these patients were operated without previous biopsy. Group B had a significantly higher rate of intralesional margins (p < 0.001), a smaller diameter of primary lesion (p = 0.007), a higher rate of additional plastic surgery after re-resection (p = 0.009) and a longer period before referral (p < 0.001) than patients treated according to treatment guidelines (group A). There was no influence on survival, local recurrence or metastasis. CONCLUSIONS: There is a need for the reduction of inadequate surgery for STS.
- Find related publications in this database (Keywords)
- Soft-tissue sarcoma
- clinical guidelines
- surgery