Selected Publication:
Zobel, G; Ring, E; Zobel, V.
Continuous arteriovenous renal replacement systems for critically ill children.
Pediatr Nephrol. 1989; 3(2):140-143
Doi: 10.1007/BF00852895
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- Co-authors Med Uni Graz
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Ring Ekkehard
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- Abstract:
- Five different arteriovenous renal replacement systems were used to treat 23 critically ill oliguric or anuric children. Slow continuous ultrafiltration (SCU) was carried out for 8 patient days, continuous arteriovenous haemofiltration (CAVH) for 40, suction-supported CAVH for 56, continuous or intermittent arteriovenous haemodiafiltration (AVHDF) for 3, and continuous arteriovenous haemodialysis (CAVHD) for 24 days. SCU allowed excellent control of fluid overload in 4 patients within 47 +/- 17 h. Urea clearances ranged from 5.6 +/- 2.1 ml/min per m2 (spontaneous CAVH) to 15.3 +/- 3.7 ml/min per m2 (CAVHD) and enabled good control of azotaemia. Ultrafiltration rates of the different filters ranged from 1.6 +/- 0.3 to 11.5 +/- 2.4 ml/min per m2. The only serious complication was a femoral artery thrombosis in a 1.5-year-old boy. Minor side-effects were local bleeding at the entrance site of the arterial catheter and transient hypotension during suction-supported CAVH. Of 23 patients, 8 died because of progressive multiple organ system failure, a mortality of 35%.
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Child, Preschool -
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Hemofiltration - adverse effects
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Humans - adverse effects
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Hypotension - etiology
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Kidney Failure, Acute - therapy
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Renal Dialysis - therapy
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Suction - therapy
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Time Factors - therapy
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Ultrafiltration - therapy