Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Richtig, E; Ahlgrimm-Siess, V; Koller, S; Gerger, A; Horn, M; Smolle, J; Hofmann-Wellenhof, R.
Follow-up of actinic keratoses after shave biopsy by in-vivo reflectance confocal microscopy--a pilot study.
J Eur Acad Dermatol Venereol. 2010; 24(3):293-298
Doi: 10.1111/j.1468-3083.2009.03410.x
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Richtig Erika
- Co-Autor*innen der Med Uni Graz
- Ahlgrimm-Siess Verena
- Gerger Armin
- Hofmann-Wellenhof Rainer
- Koller Silvia Eleonore
- Smolle Josef
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Background Monitoring of treatment efficacy after shave biopsy of actinic keratoses (AK) is often difficult, as clinical and dermoscopic features may not be reliable. Objectives We investigated the applicability of in-vivo reflectance confocal microscopy (RCM) for the follow-up of AK after shave biopsy. Methods A total of 10 lesions were investigated by RCM before shave biopsy, after 3 and 12 months by two observers in agreement blinded to location, patients and time interval. Results At baseline all lesions showed typical clinical, dermoscopic and RCM criteria of AK. Three months after shave biopsy, all lesions presented clinically as normal skin (NS), but two lesions showed features suspicious for AK by RCM. After 12 months, one lesion of these two lesions changed into NS in RCM, whereas the other lesion progressed into clinical visible AK. At baseline, the two observers diagnosed 10 of 10 lesions correctly in RCM, after 3 months eight of 10 lesions and after 12 months all lesions were diagnosed correctly. Conclusions Our results suggest that RCM might be a useful tool in the follow-up of AK after shave biopsy and might be used in inconclusive clinical and dermoscopic presentations of lesions after surgery or other treatment modalities.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Aged, 80 and over -
- Biopsy - methods
- Diagnosis, Differential -
- Disease Progression -
- Female -
- Follow-Up Studies -
- Humans -
- Keratosis, Actinic - pathology
- Male -
- Microscopy, Confocal - methods
- Pilot Projects -
- Prognosis -
- Reproducibility of Results -
- Severity of Illness Index -
- Time Factors -
- Find related publications in this database (Keywords)
- actinic keratosis
- confocal scanning laser microscopy
- non-invasive follow-up
- reflectance