Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Lenney, W; Boner, AL; Bont, L; Bush, A; Carlsen, KH; Eber, E; Fauroux, B; Götz, M; Greenough, A; Grigg, J; Hull, J; Kimpen, J; Sánchez Luna, M; de Benedictis, FM.
Medicines used in respiratory diseases only seen in children.
Eur Respir J. 2009; 34(3): 531-551.
Doi: 10.1183/09031936.00166508
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- Co-authors Med Uni Graz
- Eber Ernst
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- Abstract:
- Detailed literature searches were carried out in seven respiratory disease areas. Therapeutic evidence for efficacy of medicinal products was assessed using the Grades of Recommendation, Assessment and Evaluation (GRADE) methodology, as well as an assessment of safety and side-effects. Systemic corticosteroids may reduce the development of bronchopulmonary dysplasia but have serious side-effects. Antioxidants need further study to demonstrate whether they have long-term benefits. Treatments for acute bronchiolitis have shown little benefit but new antiviral and monoclonal antibodies need further assessment. Well-constructed studies are needed to confirm the value of inhaled corticosteroids and/or montelukast in the management of viral-induced wheeze. Corticosteroids are the treatment of choice in croup. Minimal or no information is available for the treatment of congenital lung abnormalities, bronchiolitis obliterans and interstitial lung disease.
- Find related publications in this database (using NLM MeSH Indexing)
- Age Factors -
- Anti-Bacterial Agents - therapeutic use
- Anti-Inflammatory Agents - therapeutic use
- Antioxidants - therapeutic use
- Child -
- Child, Preschool -
- Humans -
- Infant -
- Infant, Newborn -
- Infant, Premature -
- Infant, Premature, Diseases -
- Lung Diseases - drug therapy
- Respiratory System Agents - therapeutic use
- Find related publications in this database (Keywords)
- Bronchiolitis
- bronchiolitis obliterans
- bronchopulmonary dysplasia
- croup
- interstitial lung disease
- viral-induced wheeze