Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Soltysiak, P; Saxena, AK.
Micro-computed tomography for implantation site imaging during in situ oesophagus tissue engineering in a live small animal model.
J Tissue Eng Regen Med. 2009; 3(7):573-576
Doi: 10.1002/term.202
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Saxena Amulya Kumar
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- Abstract:
- For tissue engineering of gastrointestinal organs, in situ implantation of constructs in the omentum is performed to utilize the body as a bioreactor for tissue generation. In this approach, constructs are fabricated into tubes, using stents, and implanted in the omentum to induce vascularization. In order to evaluate the constructs and its environment during the period of in situ tissue engineering in the rat model, micro-computed tomography imaging was performed. Imaging using micro-computed tomography was useful in localization of the position of the construct, evaluation of implant site tissue, degree of peripheral inflammation to neighbouring tissues and migration of the implanted construct. Images also enable the estimation of the dimensions of the construct and imaging of cyst formations or fluid accumulations on the luminal side of the tubular construct or ascites formation. Since micro-computed tomography is a non-invasive method, it can be repeated for evaluation of implanted constructs if in situ tissue engineering is performed over longer periods.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Bone Substitutes -
- Equipment Design -
- Esophagus - cytology
- Inflammation -
- Omentum - metabolism
- Rats -
- Rats, Sprague-Dawley -
- Silicon - chemistry
- Stents -
- Tissue Engineering - instrumentation
- Tissue Scaffolds -
- X-Ray Microtomography - methods
- Find related publications in this database (Keywords)
- micro-computed tomography
- in situ tissue engineering
- gastrointestinal
- tubular constructs
- oesophagus
- imaging