Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Ferrara, G; Giorgio, CM; Zalaudek, I; Broganelli, P; Pellacani, G; Tomasini, C; Argenziano, G.
Sclerosing nevus with pseudomelanomatous features (nevus with regression-like fibrosis): clinical and dermoscopic features of a recently characterized histopathologic entity.
Dermatology. 2009; 219(3):202-208
Doi: 10.1159/000228317
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Zalaudek Iris
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- Abstract:
- Background: Sclerosing nevi with pseudomelanomatous features or, else, nevi with regression-like fibrosis (NRLF) are histopathologic simulators of regressing melanoma. Objective: We aimed at evaluating the clinical features in a series of NRLF. Methods: Dermoscopic images of NRLF were re-evaluated according to the amount of regression, the presence of white/blue areas and the 7-point checklist. Results: Forty-six lesions from 44 patients (M:F = 3.4:1; mean age: 42 years) were evaluated. Thirty-seven lesions were excised from the back, mostly from the scapular area. All the lesions were dermoscopically atypical, with large amounts of regression (>10% in 43 cases) and with coexistence of white and blue areas (41 cases). According to the 7-point checklist, 25 lesions were labeled as benign, probably because regression obscured other dermoscopic features of atypia. Conclusion: NRLF are mostly found in the convex area of the back. A better recognition of their clinicopathologic features can allow a more conservative management. Copyright (C) 2009 S. Karger AG, Basel
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Aged, 80 and over -
- Dermoscopy - methods
- Diagnosis, Differential -
- Female -
- Fibrosis - pathology
- Follow-Up Studies -
- Humans -
- Male -
- Melanocytes - pathology
- Melanoma - diagnosis
- Middle Aged -
- Nevus - pathology
- Sclerosis - pathology
- Young Adult -
- Find related publications in this database (Keywords)
- Dermoscopy
- Nevus regression
- Regression-like fibrosis