Medizinische Universität Graz - Research portal
Selected Publication:
Fazekas, F; Niederkorn, K; Schmidt, R; Offenbacher, H; Horner, S; Bertha, G; Lechner, H.
White matter signal abnormalities in normal individuals: correlation with carotid ultrasonography, cerebral blood flow measurements, and cerebrovascular risk factors.
Stroke. 1988; 19(10):1285-1288
Doi: 10.1161/01.STR.19.10.1285
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- Leading authors Med Uni Graz
- Fazekas Franz
- Co-authors Med Uni Graz
- Horner Susanna
- Niederkorn Kurt
- Schmidt Reinhold
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- Abstract:
- We studied 52 asymptomatic subjects using magnetic resonance imaging, and we compared age-matched groups (51-70 years old) with and without white matter lesions with respect to carotid ultrasonography, cerebral blood flow (xenon-133 injection), and cerebrovascular risk factors. In the group with white matter signal abnormalities, we noted a higher frequency of extracranial carotid artery disease, a lower mean gray matter blood flow (F1), and a significant reduction (p less than 0.05) in blood flow of the slow-flowing (F2) compartment. Hypertension, diabetes mellitus, and cardiac diseases (p less than 0.002) were found more often in this group. Our results indicate that a higher incidence of changes known to be associated with an increased risk for stroke exists in the presence of white matter lesions in normal elderly individuals.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Brain Diseases - complications
- Cerebrovascular Disorders - complications
- Humans - complications
- Magnetic Resonance Imaging - complications
- Middle Aged - complications
- Risk Factors - complications
- Ultrasonography - complications