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Gewählte Publikation:

Fazekas, F; Niederkorn, K; Schmidt, R; Offenbacher, H; Horner, S; Bertha, G; Lechner, H.
White matter signal abnormalities in normal individuals: correlation with carotid ultrasonography, cerebral blood flow measurements, and cerebrovascular risk factors.
Stroke. 1988; 19(10):1285-1288 Doi: 10.1161/01.STR.19.10.1285 [OPEN ACCESS]
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Führende Autor*innen der Med Uni Graz
Fazekas Franz
Co-Autor*innen der Med Uni Graz
Horner Susanna
Niederkorn Kurt
Schmidt Reinhold
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Abstract:
We studied 52 asymptomatic subjects using magnetic resonance imaging, and we compared age-matched groups (51-70 years old) with and without white matter lesions with respect to carotid ultrasonography, cerebral blood flow (xenon-133 injection), and cerebrovascular risk factors. In the group with white matter signal abnormalities, we noted a higher frequency of extracranial carotid artery disease, a lower mean gray matter blood flow (F1), and a significant reduction (p less than 0.05) in blood flow of the slow-flowing (F2) compartment. Hypertension, diabetes mellitus, and cardiac diseases (p less than 0.002) were found more often in this group. Our results indicate that a higher incidence of changes known to be associated with an increased risk for stroke exists in the presence of white matter lesions in normal elderly individuals.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Aged -
Brain Diseases - complications
Cerebrovascular Disorders - complications
Humans - complications
Magnetic Resonance Imaging - complications
Middle Aged - complications
Risk Factors - complications
Ultrasonography - complications

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