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Roll, P; Beham, A; Beham-Schmid, Ch.
Post-mortem histopathological investigations of the bone marrow in forensic medicine: an important issue for both the forensic and clinical pathologist.
Forensic Sci Int. 2009; 186(1-3):e17-e20
Doi: 10.1016/j.forsciint.2008.12.005
Web of Science
PubMed
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- Leading authors Med Uni Graz
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Roll Peter
- Co-authors Med Uni Graz
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Beham Alfred
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Beham-Schmid Christine
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- Abstract:
- In the forensic literature only a few scientific reports are dealing with series of histopathological bone marrow (BM) investigations, mainly concerning changes after drug abuse and alcoholic consumption. In a period of 13 years (1995-2008) we routinely investigated 225 BM specimens from anterior iliac crests taken at forensic autopsies if the cause of death was unclear or vague, septicaemia was suspected or known, in cases of presumed haemorrhagic diathesis or bleeding tendencies, spleens were found to be enlarged or intoxications were suspected or proofed. In 78 cases (34.66%) abnormal histopathologic changes were found. Forty of those revealed neoplastic, mainly haematological diseases, which were unknown during lifetime. Referring to our findings, extraction of post-mortem BM specimens for histopathological investigations should become an essential issue for both the forensic and clinical pathologist.
- Find related publications in this database (using NLM MeSH Indexing)
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Adolescent -
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Adult -
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Aged -
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Aged, 80 and over -
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Biopsy -
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Bone Marrow - pathology
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Child -
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Child, Preschool -
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Female -
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Forensic Pathology -
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Hematologic Diseases - pathology
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Humans -
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Ilium - pathology
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Immunohistochemistry -
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Infant -
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Infant, Newborn -
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Male -
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Mast Cells - pathology
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Megakaryocytes - pathology
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Middle Aged -
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Plasma Cells - pathology
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Sepsis - pathology
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Young Adult -
- Find related publications in this database (Keywords)
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Bone marrow histology
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Post-mortem investigation
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Leukaemia
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Forensic autopsy