Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Moertl, MG; Ulrich, D; Pickel, KI; Klaritsch, P; Schaffer, M; Flotzinger, D; Alkan, I; Lang, U; Schlembach, D.
Changes in haemodynamic and autonomous nervous system parameters measured non-invasively throughout normal pregnancy.
Eur J Obstet Gynecol Reprod Biol. 2009; 144 Suppl 1:S179-S183
Doi: 10.1016/j.ejogrb.2009.02.037
[Poster]
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- Führende Autor*innen der Med Uni Graz
- Mörtl Manfred Georg
- Schlembach Dietmar
- Co-Autor*innen der Med Uni Graz
- Gold ehem Ulrich Daniela
- Klaritsch Philipp
- Lang Uwe
- Mayer-Pickel Karoline Ilse
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- Abstract:
- Objective: To examine non-invasively haemodynamic and autonomous parameters throughout normal pregnancy. haemodynamic as well as autonomous parameters. 20 healthy women were included and scheduled for longitudinal examinations throughout normal pregnancy. Heart rate (HR), blood pressure (BP), stroke volume (SV), cardiac output (CO), systemic vascular resistance (SVR), heart rate variability (HRV), blood pressure variability (BPV), and baroreceptor sensitivity (BRS) were measured. Measurements were performed at gestational week 10(+0)-13(+6), 15(+0)-18(+6), 20(+0)-22(+6), and >30(+0). Results: HR increased during gestation showing a significant increase at III versus I trimester (74 bpm vs. 88 bpm, P < .05). Mean arterial pressure remained stable until III trimester, when a significant increase compared to I trimester could be noted (78 mm Hg vs. 86 mm Hg, P < .05). SV and CO remained relatively stable in I and II trimester, and in III trimester significant decreases were observed. In contrast, SVR increased significantly at III trimester (P < .001). Whereas HRV and BPV did not change at different gestational ages, BRS was significantly lower in III trimester compared to I trimester values (P < .05). Conclusion: The non-invasive determination of cardiovascular and autonomous parameters throughout pregnancy is possible and the results of this pilot study can serve as basic parameters for classifying and assessing cardiovascular and autonomous changes in pathological conditions in pregnancy such as hypertensive disorders. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Autonomic Nervous System - physiology
- Blood Pressure -
- Cardiac Output -
- Female -
- Heart Rate -
- Hemodynamics - physiology
- Humans -
- Longitudinal Studies -
- Monitoring, Physiologic -
- Pregnancy - physiology
- Find related publications in this database (Keywords)
- Cardiovascular adaptation in pregnancy
- Autonomous nervous system
- Heart rate variability
- Blood pressure variability
- Baroreceptor sensitiviy
- Task Force (R) Monitor