Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Koeppl, C; Findl, O; Menapace, R; Kriechbaum, K; Wirtitsch, M; Buehl, W; Sacu, S; Drexler, W.
Pilocarpine-induced shift of an accommodating intraocular lens: AT-45 Crystalens.
J Cataract Refract Surg. 2005; 31(7):1290-1297
Doi: 10.1016/j.jcrs.2005.03.055
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Wirtitsch Matthias
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- Abstract:
- PURPOSE: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. SETTING: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. METHODS: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. RESULTS: A slight backward shift of the IOL of 151 mum in the nonpolished group (P < .001) and 122 mum in the polished group (P < .005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. CONCLUSIONS: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.
- Find related publications in this database (using NLM MeSH Indexing)
- Accommodation, Ocular - drug effects
- Aged - drug effects
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- Ciliary Body - drug effects
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- Humans - etiology
- Lens Implantation, Intraocular - etiology
- Lenses, Intraocular - etiology
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- Miotics - adverse effects
- Muscle Contraction - drug effects
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- Pilocarpine - adverse effects
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