Gewählte Publikation:
Eyb, H; Sperger, H; Borkenstein, M; Müller, W; Passath, A.
Congenital hyperthyroidism caused by diaplacental exchange of thyrotropin receptor antibodies
KLIN PADIAT. 1988; 200(1): 74-77.
Doi: 10.1055/s-2008-1033690
(- Case Report)
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- Co-Autor*innen der Med Uni Graz
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Borkenstein Helmuth Martin
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Müller Wilhelm
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- Abstract:
- We describe the case of a premature baby, extremely small for date whose mother had an untreated hyperthyroidism during pregnancy. Severe symptoms of connatal hyperthyroidism appeared after a latency period of seven days. As the underlying cause we suggest the placental transmission of thyrotropin-receptor-antibodies (TRAb), which were elevated in the mother and the newborn. Main symptoms in the newborn were tachycardia, tachypnea, sweating and diarrhea.
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Autoantibodies - analysis
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Female - analysis
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Graves Disease - immunology
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Humans - immunology
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Hyperthyroidism - congenital
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Infant, Newborn - congenital
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Maternal-Fetal Exchange - congenital
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Pregnancy - congenital
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Receptors, Thyrotropin - immunology
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Thyroid Function Tests - immunology