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Seewann, A; Kooi, EJ; Roosendaal, SD; Barkhof, F; van der Valk, P; Geurts, JJ.
Translating pathology in multiple sclerosis: the combination of postmortem imaging, histopathology and clinical findings.
Acta Neurol Scand. 2009; 119(6):349-355
Doi: 10.1111/j.1600-0404.2008.01137.x
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PubMed
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- Führende Autor*innen der Med Uni Graz
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Seewann Alexandra
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- Seewann A, Kooi E-J, Roosendaal SD, Barkhof F, van der Valk P, Geurts JJG. Translating pathology in multiple sclerosis: the combination of postmortem imaging, histopathology and clinical findings.Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2008.01137.x. (c) 2009 The Authors Journal compilation (c) 2009 Blackwell Munksgaard. Studies combining postmortem magnetic resonance imaging (MRI) and histopathology have provided important insights into the abnormalities reflected by MRI. A short overview of these studies applied to multiple sclerosis (MS) is provided in this review, and the Amsterdam postmortem imaging protocol is specifically highlighted. Postmortem MRI and histopathology correlation studies have enabled a direct translation of basic pathology in MS to the clinical setting, and have simultaneously served as a biological validation of new MRI techniques.
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Brain - pathology
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Diagnostic Imaging -
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Humans -
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Magnetic Resonance Imaging - methods
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Multiple Sclerosis - pathology
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Postmortem Changes -
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postmortem imaging
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multiple sclerosis
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histopathology
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magnetic resonance imaging