Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kofler, K; Leitinger, G; Kristler, M; Saxena, AK.
Smooth muscle tissue engineering for hybrid tubular organs: scanning electron microscopic investigations of cell interactions with collagen scaffolds.
J Tissue Eng Regen Med. 2009; 3(4): 321-324.
Doi: 10.1002/term.171
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Kofler Kristina
- Saxena Amulya Kumar
- Co-Autor*innen der Med Uni Graz
- Leitinger Gerd
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- Abstract:
- Tissue engineering of transplantable tubular tissue necessitates a composite approach to assembling the individual components. In the engineering of tubular structures (gastrointestinal, urogenital and vascular tissues) there is a demand for smooth muscle tissue in addition to the primary organ-specific tissue. This study aims to investigate the interaction of smooth muscle cells on bovine collagen scaffolds cross-linked with glutaraldehyde under in vitro conditions, using scanning electron microscopy. The density of tissue generated over the 8 week period was demonstrated in terms of: (a) scaffold coverage and attachment; (b) cell density; (c) cell viability deep inside the scaffolds; and (d) cell differentiation.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Cattle -
- Cell Differentiation -
- Collagen - metabolism
- Microscopy, Electron, Scanning - methods
- Muscle, Smooth - cytology
- Tissue Engineering -
- Find related publications in this database (Keywords)
- scanning electron microscopy
- smooth muscle
- collagen
- static culture
- viability
- differentiation