Medizinische Universität Graz - Research portal
Selected Publication:
Borkenstein, M.
Intranasal LH-RH for cryptorchidism: response to initial treatment and to treatment after relapse.
EUR J PEDIAT. 1987; 146 Suppl 2(3): S42-S43.
Doi: 10.1007/BF00452870
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- Leading authors Med Uni Graz
- Borkenstein Helmuth Martin
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- Abstract:
- Fifty-three prepubertal boys with unilateral (n = 38) or bilateral (n = 15) cryptorchidism were treated for 4 weeks with synthetic LH-RH (Cryptocur, Hoechst) 1.2 mg daily, divided into 3 X 400 micrograms and administered intranasally. Complete descent was observed in 54% of testes--37% in the boys with unilateral cryptorchidism and 77% in the boys with bilateral cryptorchidism. Follow-up examination 6 months after therapy showed relapse in 30%, and a second therapeutic trial with intranasal LH-RH was effective in all these cases. Treatment of cryptorchidism with intranasal synthetic LH-RH, 3 X 400 micrograms/day, seems to be very effective, painless and without major side effects. However, follow-up is mandatory.
- Find related publications in this database (using NLM MeSH Indexing)
- Administration, Intranasal -
- Child -
- Child, Preschool -
- Cryptorchidism - drug therapy
- Follow-Up Studies - drug therapy
- Gonadotropin-Releasing Hormone - administration and dosage
- Humans - administration and dosage
- Male - administration and dosage
- Recurrence - administration and dosage