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Gewählte Publikation:

Groener, JE; Kostner, GM.
Lipid transfer protein-catalyzed exchange of cholesteryl ester between high density lipoproteins and apoB-containing lipoproteins.
J Lipid Res. 1987; 28(9):1053-1056 Doi: 10.1016/S0022-2275(20)38614-4
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Co-Autor*innen der Med Uni Graz
Kostner Gerhard
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Abstract:
Low density lipoproteins (LDL), lipoprotein (a)(Lp(a)), and lipoprotein(a) after removal of the a-protein (Lp(a-)) were compared with respect to their ability to accept cholesteryl ester from high density lipoproteins (HDL). The incubations were performed at constant concentrations of HDL and various concentrations of either LDL, Lp(a), or Lp(a-). Lp(a) exchanged cholesteryl ester with HDL, but at a rate that was only 48.5 +/- 3.8% of the exchange rate found in the presence of autologous LDL. Cleavage of the apo(a) from Lp(a) resulted in Lp(a-), an LDL-like particle, with characteristics of cholesteryl ester exchange very similar to LDL.
Find related publications in this database (using NLM MeSH Indexing)
Apolipoproteins B - blood
Carrier Proteins - pharmacology
Catalysis - pharmacology
Cholesterol Esters - blood
Cholesterol, HDL - blood
Energy Transfer - drug effects
Humans - drug effects
Lipoprotein(a) - drug effects
Lipoproteins - blood
Lipoproteins, HDL - blood
Lipoproteins, LDL - blood

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