Gewählte Publikation:
Groener, JE; Kostner, GM.
Lipid transfer protein-catalyzed exchange of cholesteryl ester between high density lipoproteins and apoB-containing lipoproteins.
J Lipid Res. 1987; 28(9):1053-1056
Doi: 10.1016/S0022-2275(20)38614-4
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- Co-Autor*innen der Med Uni Graz
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Kostner Gerhard
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- Abstract:
- Low density lipoproteins (LDL), lipoprotein (a)(Lp(a)), and lipoprotein(a) after removal of the a-protein (Lp(a-)) were compared with respect to their ability to accept cholesteryl ester from high density lipoproteins (HDL). The incubations were performed at constant concentrations of HDL and various concentrations of either LDL, Lp(a), or Lp(a-). Lp(a) exchanged cholesteryl ester with HDL, but at a rate that was only 48.5 +/- 3.8% of the exchange rate found in the presence of autologous LDL. Cleavage of the apo(a) from Lp(a) resulted in Lp(a-), an LDL-like particle, with characteristics of cholesteryl ester exchange very similar to LDL.
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Lipoproteins - blood
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