Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Lipp, RW; Schnedl, WJ; Hammer, HF; Kotanko, P; Leb, G; Krejs, GJ.
Evidence of accelerated gastric emptying in longstanding diabetic patients after ingestion of a semisolid meal.
J Nucl Med. 1997; 38(5):814-818
[OPEN ACCESS]
Web of Science
PubMed
Google Scholar
- Führende Autor*innen der Med Uni Graz
- Lipp Rainer
- Co-Autor*innen der Med Uni Graz
- Hammer Heinz
- Krejs Günter Josef
- Leb Georg
- Schnedl Wolfgang
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Abstract:
- This study investigated the prevalence of accelerated gastric emptying in 40 consecutive nonselected patients with longstanding insulin-dependent diabetes mellitus (range 11-54 yr; mean 27 yr). The gastric emptying of a semisolid meal labeled with 99mTc was continuously recorded with a dual-head gamma camera for 90 min in patients who were supine. Eleven patients demonstrated delayed gastric emptying, but three male diabetics showed accelerated gastric emptying with retention values that were different from controls already after 10 min of recording (89% +/- 3% versus 96% +/- 4%; p < 0.02). During the 90-min segment, accelerated gastric emptying reduced initial gastric contents to 11% +/- 8% (p < 0.001) as compared to 50% +/- 10% in control subjects and 78% +/- 6% (p < 0.001) in patients with delayed gastric emptyings. Accelerated gastric emptying was characterized by an almost equal initial meal distribution in proximal and distal compartments of stomach, both emptying approximately 90% of their contents within 90 min. Normal and delayed gastric emptying was characterized by a 60%-40% initial ratio of meal distribution between gastric compartments. During normal emptying, both compartments reduced contents with approximately 50%, but delayed gastric emptying was caused by only a 15% reduction of proximal contents accompanied by a 34% reduction in distal contents. Recording in the supine position to abolish gravitational influences demonstrated accelerated gastric emptying of a firm semisolid meal with a prevalence of 8%. However, delayed gastric emptying was shown as the predominant gastric manifestation of longstanding insulin-dependent diabetes mellitus with a prevalence of 28%.
- Find related publications in this database (using NLM MeSH Indexing)
- Case-Control Studies -
- Diabetes Mellitus, Type 1 - complications
- Diabetes Mellitus, Type 1 - diagnostic imaging
- Diabetes Mellitus, Type 1 - physiopathology
- Female -
- Food -
- Gastric Emptying - physiology
- Gastroparesis - etiology
- Humans -
- Male -
- Middle Aged -
- Radionuclide Imaging -
- Stomach - diagnostic imaging
- Supine Position -
- Technetium -
- Time Factors -
- Find related publications in this database (Keywords)
- Accelerated Gastric Emptying
- Insulin-Dependent Diabetes Mellitus
- Supine Position
- Semisolid Test Meal