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Reisinger, EC; Fritzsche, C; Krause, R; Krejs, GJ.
Diarrhea caused by primarily non-gastrointestinal infections.
Nat Clin Pract Gastroenterol Hepatol. 2005; 2(5): 216-222. Doi: 10.1038/ncpgasthep0167 [OPEN ACCESS]
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Co-Autor*innen der Med Uni Graz
Krause Robert
Krejs Günter Josef
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Abstract:
Infectious diseases that do not primarily affect the gastrointestinal tract can cause severe diarrhea. The pathogenesis of this kind of diarrhea includes cytokine action, intestinal inflammation, sequestration of red blood cells, apoptosis and increased permeability of endothelial cells in the gut microvasculature, and direct invasion of gut epithelial cells by various infectious agents. Of the travel-associated systemic infections presenting with fever, diarrhea occurs in patients with malaria, dengue fever and SARS. Diarrhea also occurs in patients with community-acquired pneumonia, when it is suggestive of legionellosis. Diarrhea can also occur in patients with systemic bacterial infections. In addition, although diarrhea is rare in patients with early Lyme borreliosis, the incidence is higher in those with other tick-borne infections, such as ehrlichiosis, tick-borne relapsing fever and Rocky Mountain spotted fever. Unfortunately, it is often not established whether diarrhea is an initial symptom or develops during the course of the disease. The real incidence of diarrhea in some infectious diseases must also be questioned because it could represent an adverse reaction to antibiotics.
Find related publications in this database (using NLM MeSH Indexing)
Diarrhea - etiology
Humans -
Malaria - complications
Severe Acute Respiratory Syndrome - complications
Severe Dengue - complications
Tick-Borne Diseases - complications

Find related publications in this database (Keywords)
antibiotic-associated diarrhea
malaria
pneumonia
primarily non-gastrointestinal infecti
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