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SHR Neuro Cancer Cardio Lipid Metab Microb
Van Mieghem, T; Deprest, J; Klaritsch, P; Gucciardo, L; Done', E; Verhaeghe, J; Lewi, L.
Ultrasound prediction of intertwin birth weight discordance in monochorionic diamniotic twin pregnancies.
Prenat Diagn. 2009; 29(3):240-244
Doi: 10.1002/pd.2212
Web of Science
PubMed
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FullText_MUG
- Co-authors Med Uni Graz
- Klaritsch Philipp
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- Abstract:
- Objectives To estimate the accuracy of ultrasound to predict birth weight (BW) and BW discordance in monochorionic diamniotic (MCDA) twin pregnancies. Methods A prospective series of MCDA twin pregnancies was subjected to ultrasound fetal weight estimations (EFW) at 16, 20, and 26 weeks of gestation and within 2 weeks of birth. Intertwin weight discordance (Delta EFW and Delta BW) was calculated. The correlation between Delta EFW, Delta BW, EFW, and BW was assessed (Pearson) and least square regression analysis was performed. Positive and negative predictive values of ultrasound to detect severe Delta BW were calculated. Receiver-operating characteristics (ROC) curves were constructed to predict Delta BW >25% at different time points of gestation. Results Sixty pregnancies were included. Median Delta BW was 9.98%. Ten(16,7%), 8(13,3%) and 5(8,3%) twin pairs had a Delta BW > 20%, > 25% and > 30%, respectively. BW and EFW (r = 0.96: p < 0.001) as well as Delta BW and Delta EFW were well correlated with each other (r = 0.75; p < 0.001). Bland-Altman analysis showed that ultrasound evaluation overestimated Delta BW if > 20%. Negative predictive value of ultrasound for Delta BW >25% was 98%. The area under the curve (AUC) to predict a Delta BW >25% at 16, 20, and 26 weeks and < 2 weeks before birth was 0.79, 0.87, 0.93, and 0.95, respectively. Conclusions Ultrasound estimations of BW and Delta BW are highly correlated with actual BW and Delta BW in MCDA twin pregnancies. Copyright (C) 2009 John Wiley & Sons, Ltd.
- Find related publications in this database (using NLM MeSH Indexing)
- Birth Weight -
- Female -
- Fetal Weight -
- Humans -
- Longitudinal Studies -
- Predictive Value of Tests -
- Pregnancy -
- Prospective Studies -
- ROC Curve -
- Twins, Monozygotic -
- Ultrasonography, Prenatal -
- Find related publications in this database (Keywords)
- monochorionic twins
- ultrasound
- prediction
- birth weight discordance
- growth