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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Baumann, A; Schweiger, S; Schweiger, W; Tomka, M; Thalhammer, M; Baumann, G; Cohnert, T.
Vascular leiomyosarcoma-Diagnostic procedures, therapy and prognosis.
GEFASSCHIRURGIE. 2008; 13(6): 421-425.
Doi: 10.1007/s00772-008-0610-z
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- Leading authors Med Uni Graz
- Baumann Anneliese
- Co-authors Med Uni Graz
- Cohnert Tina Ulrike
- Schweiger Stephan
- Thalhammer Michael
- Tomka Maurice
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- Abstract:
- Vascular leiomyosarcoma (LMS) is a rare soft tissue tumor that originates in the smooth muscle cells of the vascular media. It occurs most frequently in the 5th and 6th decades of life. Vascular LMS occurs five times more frequently in the large veins than in arteries, and in 60% in the vicinity of the inferior vena cava (VCI); women are afflicted in 80% of cases. These tumors grow expansively, displacing and compressing other organs and causing uncharacteristic symptoms. Diagnosis can be made with computer tomography or magnetic resonance tomography. Opinions vary on preoperative polychemotherapy (PCT). Radical surgical resection is at present the only treatment that has a favorable influence on long-term survival. Surgical options include tangential resection of the tumor and the involved segment of the vena cava with or without patch plastic, tumor resection and interposition of a Goretex (R) prosthesis, or resection and ligation of the VCI when a thrombosis has been diagnosed preoperatively. Postoperative chemotherapy is said to reduce local recurrences. These rare and highly malignant tumors have a poor prognosis, with a 5-year survival rate for curatively operated patients of 28%. Diagnosis, treatment and prognosis are discussed on the basis of three cases.
- Find related publications in this database (Keywords)
- Vascular leimyosarcoma (LMS)
- Inferior vena cava (VCI)