Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Seliger, H; Bader, R; BirchHirschfeld, E; FoldesPapp, Z; Guhrs, KH; Hinz, M; Rosch, R; Scharpf, C.
Surface reactive polymers for special applications in nucleic acid synthesis
REACT FUNCT POLYM. REACTIVE & FUNCTIONAL POLYMERS; 26: 119-126. ( Presented at: 6th International Conference on Polymer Supported Reactions in Organic Chemistry (POC 94), VENICE, ITALY, JUN 19-23, 1994)
Doi: 10.1016/1381-5148(95)00059-O
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- Co-Autor*innen der Med Uni Graz
- Földes-Papp Zeno
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- Abstract:
- This publication reviews work done in the authors' laboratories on the functionalization of surface-reactive polymers and their application as a basis for the preparation of oligonucleotides of extended length, larger number or quantity. In addition to nonporous particulate materials (silicagel microbeads; polystyrene-grafted polytetrafluoroethylene particles) special focus is on recent work describing the introduction of spacered amino groups into polypropylene films and the preparation of oligonucleotides on polypropylene surface. A prototype apparatus is shown, for use with a four-column DNA synthesizer, that permits the semi-mechanized preparation of a one-dimensional array of oligonucleotides of variant sequence.
- Find related publications in this database (Keywords)
- surface-reactive polymers
- nucleic acid synthesis