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Petru, E; Benedicic, C; Kimmig, R; Marth, C.
Early ovarian cancer (FIGO stage I-IIA)
ONKOLOGE. 2008; 14(11): 1130-+.
Doi: 10.1007/s00761-008-1472-4
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- Leading authors Med Uni Graz
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Petru Edgar
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- Abstract:
- About 25% and 7% of ovarian cancer patients are diagnosed as having FIGO stage I or IIA disease, respectively. If the suspicion of ovarian cancer exists, operative exploration and histologic confirmation are necessary. It is almost never possible to preoperatively diagnose ovarian cancer at an early stage. For example, if only one positive lymph node in the paraaortic region is diagnosed at final histology, the patient will be allocated to stage IIIC disease. In stages I and II disease in which ovarian cancer is limited to the pelvis, accurate surgical staging leads to upstaging of the disease to stage III in 31% of cases because of subclinical metastases in the greater omentum, the peritoneum, and/or retroperitoneal lymph nodes. Primary surgery comprises operative staging via midline laparotomy and radical surgery with the intent to accurately diagnose the extent of the disease and to resect all visible disease in the pelvis and abdomen, including a pelvic and paraaortic lymphadenectomy. Unfavorable prognostic factors in FIGO stage I disease mainly include intraoperative rupture of the capsule of the tumor as well as tumor grading of G3.
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Ovarialkarzinom
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Operatives Staging
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FIGO-Stadium
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Lymphadenektomie
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Prognose
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Ovarian cancer
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Operative staging
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FIGO stage
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Lymphadenectomy
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Prognosis