Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

Zobel, G; Müller, WD; Pürstner, P.
Glucose tolerance in intensive care premature infants with a birth weight below 1,500 g in the first 5 days
MONATSSCHR KINDERHEILK. 1986; 134(5): 253-256.
Web of Science PubMed

Co-Autor*innen der Med Uni Graz: Müller Wilhelm; Pürstner Peter
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Abstract:: Plasma insulin and blood glucose values were studied in 11 stressed premature infants with birth weight below 1 500 g during the first five days after birth under increasing fluid and glucose infusion rates. The group 11 small premature neonates was subdivided; group A consisted of 6 stressed premature infants with respiratory distress syndrome (RDS stage III-IV) and/or intraventricular haemorrhage (IVH stage III-IV), and group B of 5 slightly stressed premature infants with RDS (stage I-II and/or IVH (stage I-II). During the first two days there was no difference in caloric and fluid intake in both groups. From the third day on caloric intake was much higher in group B than in group A (day 5: group A: 61.33 +/- 13.01 kcal/kg BW; group B: 78.2 +/- 18.49 kcal/kg BW). Plasma insulin values increased in both groups during the first five days after birth (group A: day 1: mean plasma insulin values 8.18 +/- 7.59 microU/ml; day 4: 27.22 +/- 32.85 microU/ml; group B: day 1: mean plasma insulin values 4.34 +/- 2.62; day 4: 11.18 +/- 8.38). Blood glucose and plasma insulin values were significantly higher in group A than in group B. Conclusion: Impaired glucose utilisation in severely stressed premature infants with parenteral nutrition might be due to stress induced peripheral insulin resistance.
Find related publications in this database (using NLM MeSH Indexing): Birth Weight -; Blood Glucose - metabolism; Humans - metabolism; Hyperglycemia - blood; Infant, Newborn - blood; Infant, Premature, Diseases - blood; Insulin - blood; Intensive Care Units, Neonatal - blood; Parenteral Nutrition, Total - blood; Respiratory Distress Syndrome, Newborn - blood