Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Lahousen, M.
Predictive value of a tumor marker combination for the monitoring of ovarian cancer
WIEN KLIN WOCHENSCHR. 1986; 98(10): 319-325.
Web of Science
PubMed
- Führende Autor*innen der Med Uni Graz
- Lahousen Manfred
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- Abstract:
- The tumour markers carcinoembryonic antigen (CEA), ferritin, cancer antigen 125 (CA 125) and tissue polypeptide antigen (TPA) were measured by radioimmunoassay in sera from 80 patients with ovarian cancer pre-operatively, postoperatively, during cytostatic chemotherapy and on follow up. Discriminant analysis was applied to obtain retrospective classification of 60 patients into a group showing a favourable course of the disease (no recurrence, tumour regression) and into a group with an unfavourable course (recurrence, progression of the tumour). The classification was based on the introduction of the Cutting Score. By means of this bio-mathematical model it was possible to make at least a short-term prognostic statement in a further 20 patients. It is suggested that invasive diagnostic procedures may not be required in patients who are found to have normal tumour marker levels.
- Find related publications in this database (using NLM MeSH Indexing)
- Antigens, Neoplasm - analysis
- Antigens, Tumor-Associated, Carbohydrate - analysis
- Carcinoembryonic Antigen - analysis
- Combined Modality Therapy - analysis
- Female - analysis
- Ferritins - blood
- Humans - blood
- Lymphatic Metastasis - blood
- Neoplasm Recurrence, Local - diagnosis
- Neoplasm Staging - diagnosis
- Ovarian Neoplasms - diagnosis
- Peptides - analysis
- Prognosis - analysis
- Radioimmunoassay - analysis
- Tissue Polypeptide Antigen - analysis