Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Khalil, M; Enzinger, C; Wallner-Blazek, M; Scarpatetti, M; Barth, A; Horn, S; Reiter, G.
Epstein-Barr virus encephalitis presenting with a tumor-like lesion in an immunosuppressed transplant recipient.
J Neurovirol. 2008; 14(6):574-578
Doi: 10.1080/13550280802345715
(- Case Report)
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Khalil Michael
- Co-Autor*innen der Med Uni Graz
- Barth Alain
- Enzinger Christian
- Horn Sabine
- Reiter Gudrun
- Scarpatetti Michael
- Wallner-Blazek Mirja
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- Abstract:
- Epstein-Barr virus (EBV) associated central nervous system (CNS) infection is a rare disease. We report an atypical manifestation of EBV encephalitis initially presenting with a tumor-like lesion of the optic tract in an immunocompromised patient 8 years after a combined kidney and pancreas transplantation had been performed. Polymerase chain reaction (PCR) in the cerebrospinal fluid (CSF) and antibody testing confirmed the diagnosis of EBV encephalitis, most likely as a consequence of a reactivated persistent EBV infection. After cessation of the immunosuppressive therapy and induction of treatment with ganciclovir, clinical and magnetic resonance imaging (MRI) findings rapidly improved.
- Find related publications in this database (using NLM MeSH Indexing)
- Antiviral Agents - therapeutic use
- Brain Neoplasms - diagnosis
- Brain Neoplasms - surgery
- DNA, Viral - blood
- DNA, Viral - cerebrospinal fluid
- Diagnosis, Differential -
- Encephalitis, Viral - diagnosis
- Encephalitis, Viral - drug therapy
- Epstein-Barr Virus Infections - diagnosis
- Epstein-Barr Virus Infections - drug therapy
- Epstein-Barr Virus Infections - pathology
- Female -
- Ganciclovir - therapeutic use
- Glioma - diagnosis
- Glioma - surgery
- Herpesvirus 4, Human - genetics
- Herpesvirus 4, Human - isolation & purification
- Humans -
- Immunocompromised Host -
- Immunosuppressive Agents - adverse effects
- Immunosuppressive Agents - therapeutic use
- Kidney Transplantation - adverse effects
- Kidney Transplantation - immunology
- Magnetic Resonance Imaging -
- Middle Aged -
- Pancreas Transplantation - adverse effects
- Pancreas Transplantation - immunology
- Visual Pathways - pathology
- Withholding Treatment -
- Find related publications in this database (Keywords)
- brain tumor
- Epstein-Barr virus
- encephalitis
- transplantation