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Decrinis, M; Doder, S; Stark, G; Pilger, E.
A prospective evaluation of sensitivity and specificity of the ankle/brachial index in the follow-up of superficial femoral artery occlusions treated by angioplasty.
Clin Investig. 1994; 72(8):592-597 Doi: 10.1007/BF00227451
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Co-authors Med Uni Graz: Pilger Ernst
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Abstract:: The aim of this study was to provide estimates of sensitivity and specificity of clinical history, pulses, and ankle/brachial index (ABI) in the follow-up of atherosclerotic occlusions of the superficial femoral artery treated by peripheral transluminal angioplasty (PTA). A total of 116 patients were followed prospectively for 1 year after angioplasty with follow-up visits immediately after angioplasty, and at 3, 6, and 12 months. All patients underwent digital subtraction angiography after 1 year of if they reported a deterioration of their symptoms. Reobstruction was defined as reocclusion or as restenosis exceeding 70%. Patency rates were calculated separately by clinical and ankle/brachial criteria; sensitivity and specificity were derived using angiography as standard. The presence or absence of pulses distal to the treated vessel segment had a sensitivity of 78% and a specificity of 66% for a reocclusion or significant restenosis; subjective complaints evaluated by history had a sensitivity of 83% and a specificity of 51%. The sensitivity of the ABI was 72% and 66%, with a specificity of 82% and 100% for cutoff values of 0.10 and 0.15, respectively. One year after PTA the angiographic patency rate was 39% +/- 5%; the patency rate based on ABI criteria 34% +/- 5%. A deterioration in the ABI by 0.15 indicated with reasonable certainty a reocclusion or significant restenosis whereas the sensitivity of the ABI was poor in detecting significant restenosis after PTA of occlusions of the superficial femoral artery. When only clinical criteria were used, the true patency rate was significantly overestimated as more than half of all reobstructions remained asymptomatic.
Find related publications in this database (using NLM MeSH Indexing): Angiography, Digital Subtraction -; Angioplasty, Balloon -; Ankle - blood supply; Arm - blood supply; Arterial Occlusive Diseases - diagnosis; Blood Pressure Determination - diagnosis; Evaluation Studies - diagnosis; Femoral Artery - radiography; Follow-Up Studies - radiography; Humans - radiography; Popliteal Artery - radiography; Predictive Value of Tests - radiography; Prospective Studies - radiography; Pulse - radiography; Recurrence - radiography; Regional Blood Flow - radiography; Sensitivity and Specificity - radiography
Find related publications in this database (Keywords): Peripheral Arterial Obstructive Disease; Angioplasty; Ankle/Brachial Index; Sensitivity; Specificity