Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Smolle, J.
T-zone histiocytes in granulomatous skin diseases.
Dermatologica. 1985; 171(5):316-320
Doi: 10.1159/000249444
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- Führende Autor*innen der Med Uni Graz
- Smolle Josef
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- Abstract:
- We investigated the distribution of T-zone histiocytes by immunohistochemical demonstration of S-100 protein in granulomatous skin diseases (granuloma annulare, 8 cases; necrobiosis lipoidica, rheumatoid nodule, sarcoidosis, lupus vulgaris, and foreign-body granuloma; 5 cases each). T-zone histiocytes were regularly found in the lymphohistiocytic mantle, but also occasionally between epitheloid cells. Our results show that, besides the monocyte-macrophage system, T-zone histiocytes consistently contribute to the formation of cutaneous granulomas. These findings may indicate a role of delayed-type hypersensitivity.
- Find related publications in this database (using NLM MeSH Indexing)
- Foreign-Body Reaction - pathology
- Granuloma - pathology
- Histiocytes - immunology
- Humans - immunology
- Immunoenzyme Techniques - immunology
- Lupus - pathology
- Necrobiosis Lipoidica - pathology
- S100 Proteins - analysis
- Sarcoidosis - pathology
- Skin - analysis
- Skin Diseases - pathology