Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

Tritthart, HA; Koidl, B.
Comparison of electrophysiological properties of embryonic and adult heart cells.
Basic Res Cardiol. 1985; 80 Suppl 2(1):55-59
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Führende Autor*innen der Med Uni Graz
Tritthart Helmut
Co-Autor*innen der Med Uni Graz
Koidl Bernd
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Abstract:
Almost any membrane or structural property of cultured embryonic heart cells is identical to that of nodal pacemaker cells in the adult myocardium. The present electrophysiological data show that single cultured cells are advantageous to the study of cardiac impulse generation. Evidence is presented for the presence of a Na/K pump system, the dominant role of the slow Ca-inward current in excitation but not in automaticity and the susceptibility of automaticity to changes in membrane potential induced by current injection.
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Action Potentials -
Aging -
Animals -
Calcium - metabolism
Cell Membrane Permeability - metabolism
Cell Separation - metabolism
Cells, Cultured - metabolism
Electrophysiology - metabolism
Embryo - metabolism
Guinea Pigs - metabolism
Ion Channels - physiology
Myocardium - cytology
Phylogeny - cytology
Potassium - metabolism
Rats - metabolism
Sodium - metabolism

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