Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Petritsch, W; Leb, G; Passath, A; Goebel, R; Pristautz, H.
Influence of calcitonin on serum levels of pancreatic polypeptide in man.
Z Gastroenterol. 1985; 23(3):143-148
Web of Science
PubMed
- Führende Autor*innen der Med Uni Graz
- Petritsch Wolfgang
- Co-Autor*innen der Med Uni Graz
- Leb Georg
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- Abstract:
- In groups of 8 patients each, the increases in pancreatic polypeptide (hPP) serum level were measured after a protein-rich test-meal; one group received an infusion of 200 IU Salmon-calcitonin for a period of 3 hour while the other group did not. Calcitonin causes a significant inhibition of both the basal and the stimulated hPP serum level. Among the patients who did not receive a calcitonin infusion, the stimulated values after 15 to 120 minutes were significantly higher than the initial values, while patients receiving calcitonin did not show a significant increase. With calcitonin, the area under the secretion curve was 43% smaller. yet, on the basis of our results, the known gastrointestinal effects of calcitonin on pancreas secretion cannot be completely explained by the observed inhibition of hPP secretion.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Calcitonin - pharmacology
- Dietary Carbohydrates - metabolism
- Dietary Fats - metabolism
- Dietary Proteins - metabolism
- Female -
- Humans -
- Male -
- Pancreatic Polypeptide - blood
- Radioimmunoassay -