Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Kurtcuoglu, V; Soellinger, M; Summers, P; Boomsma, K; Poulikakos, D; Boesiger, P; Ventikos, Y.
Reconstruction of cerebrospinal fluid flow in the third ventricle based on MRI data.
Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv. 2005; 8(Pt 1):786-793 Doi: 10.1007/11566465_97
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Co-Autor*innen der Med Uni Graz: Söllinger Michaela
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Abstract:: A finite-volume model of the cerebrospinal fluid (CSF) system encompassing the third ventricle and the aqueduct of Sylvius was used to reconstruct CSF velocity and pressure fields based on MRI data. The flow domain geometry was obtained through segmentation of MRI brain anatomy scans. The movement of the domain walls was interpolated from brain motion MRI scans. A constant pressure boundary condition (BC) was specified at the foramina of Monro. A transient velocity BC reconstructed from velocimetric MRI scans was employed at the inferior end of the aqueduct of Sylvius. It could be shown that a combination of MRI scans and computational fluid dynamics (CFD) simulation can be used to reconstruct the flow field in the third ventricle. Pre-interventional knowledge of patient-specific CSF flow has the potential to improve neurosurgical interventions such as shunt placement in case of hydrocephalus.
Find related publications in this database (using NLM MeSH Indexing): Adult -; Algorithms -; Cerebrospinal Fluid - cytology; Computer Simulation - cytology; Humans - cytology; Image Enhancement - methods; Image Interpretation, Computer-Assisted - methods; Imaging, Three-Dimensional - methods; Magnetic Resonance Imaging, Cine - methods; Male - methods; Models, Biological - methods; Reproducibility of Results - methods; Rheology - methods; Sensitivity and Specificity - methods; Third Ventricle - anatomy and histology