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Weger, M; Haas, A.
Differential diagnosis and treatment of retinal vascular occlusion
SPEKTRUM AUGENHEILKD. 2007; 21(2): 118-127.
Doi: 10.1007/s00717-007-0197-x
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- Führende Autor*innen der Med Uni Graz
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Haas Anton
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Weger Martin
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- Abstract:
- Retinal vascular occlusions are usually not a diagnostic challenge, but similar funduscopic changes are caused by ocular ischemic syndrome, Purtscher's retinopathy, hematological diseases, diabetes or by systemic hypertension. A medical workup and the treatment of risk factors should be the first step in patients with retinal vascular occlusions to reduce the increased cardiovascular morbidity and mortality and to prevent occlusions on the fellow eye. Although retinal vein occlusions are a well established clinical entity, their management remains highly confusing and controversial. Therapeutic interventions are limited to the treatment of complications. Only photocoagulation in the treatment of iris and retinal neovascularisations and of macular edema in branch retinal vein occlusion has been proven to be an effective therapy. New therapies like radial optic neurotomy, intravitreal application of steroids or anti-VEGF substances have shown beneficial functional and morphological effects in small case series, but they have not been tested by large, well designed, prospective, randomised controlled trials. The initial management of retinal artery occlusion is similar to that of vein occlusions. It is very important to differentiate between nonarteritic and arteritic retinal artery occlusion, because the latter has to be treated with steroids. To evaluate the effect of a selective lysis with rt-PA a multicenter study has been started.
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retinal artery occlusion
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retinal vein occlusion
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differential diagnosis
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treatment