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Uranüs, S; Kronberger, L; Beham, A; Neumayer, K; Kröll, W; Aktuna, D.
New organ-preserving technics for third-grade splenic trauma. An experimental study
Z Exp Chir Transplant Kunstliche Organe. 1990; 23(1): 7-13.
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Leading authors Med Uni Graz: Uranüs Selman
Co-authors Med Uni Graz: Kröll Wolfgang
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Abstract:: We studied two new techniques for orthotopic preservation of the spleen in an animal model with respect to their technical feasibility and their hemostatic efficacy. This study was performed in two stages. In the first, the treatment of central bursting ruptures by splenorrhaphy using a resorbable compressive mesh was tested. 20 sheep have been used for this part of the study. They were divided into four groups (A: control, B: sham operation, C: splenectomy, D: mesh splenorrhaphy). Following completion of this stage, two animals from group A and two from group B were used to test a second experimental setting. Experimental trauma corresponding to isolated third degree polar rupture of the spleen was induced. This was then treated by a polar resection using stapling instruments. All animals from each stage were subjected to spleen scanning three months postoperatively, followed by splenectomy. The spleens were then examined histologically. Both macroscopically and microscopically normal splenic tissue was found. No difference between the different groups could be detected by laboratory investigations. Gamma-globulins and total serum proteins were within normal ranges after five weeks. Splenic scan revealed an excellent function of the pulp. Both techniques are distinguished by their facility and rapidity, as well as reliable hemostasis and minimal technical prerequisites.
Find related publications in this database (using NLM MeSH Indexing): Animals -; Blood Proteins - analysis; Disease Models, Animal - analysis; Female - analysis; Hemostasis, Surgical - analysis; Male - analysis; Rupture - analysis; Sheep - analysis; Spleen - injuries; Surgical Mesh - injuries; Surgical Staplers - injuries; gamma-Globulins - analysis